Prof. Dr. Meinhard Kieser

Selected Publications

2020 2019 2018 2017 2016 2015 2014 2013 2012 2011

In Press

Proctor T, Jensen K, Kieser M (2019). Integrated evaluation of targeted and non-targeted therapies in a network meta-analysis. Biometrical Journal. (accepted).
Schönenberger S, Löwhagen-Hendén P, Simonsen C.Z, Uhlmann L, Klose C, Pfaff J, Yoo A.J, Sørensen L.H, Ringleb P.A, Wick W, Kieser M, Möhlenbruch M.A, Rasmussen M, Rentzos A, Bösel J (2019). Effect of standardized general anesthesia vs. conscious sedation during thrombectomy for anterior circulation ischemic stroke on long-term functional outcome: meta-analysis of individual patient data from clinical trials randomized for peri-interventional sedation. J'AMA. (accepted).
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2020
Götte H, Kirchner M, Kieser M (2020). Adjustment for exploratory cut-off selection in randomized clinical trials with survival endpoint.Biom J 62/3:627-642.
Herrmann C, Pilz M, Kieser M, Rauch G (2020). A new conditional performance score for the evaluation of adaptive group sequential designs with sample size recalculation.Stat Med 39/15:2067-2100.
Kitzerow J, Hackbusch M, Jensen K, Kieser M, Noterdaeme M, Frohlich U, Taurines R, Geissler J, Wolff N, Roessner V, Bast N, Teufel K, Kim Z, Freitag C.M (2020). Study protocol of the multi-centre, randomised controlled trial of the Frankfurt Early Intervention Programme A-FFIP versus early intervention as usual for toddlers and preschool children with Autism Spectrum Disorder (A-FFIP study).Trials 21/1:217.
Kunzmann K, Kieser M (2020). Optimal adaptive single-arm phase II trials under quantified uncertainty.Journal of Biopharmaceutical Statistics 30/1:89-103.
Kuon J, Hommertgen A, Krisam J, Lasitschka F, Stenzinger A, Blasi M, Bozorgmehr F, Maenz M, Kieser M, Schneider M, Thomas M (2020). Durvalumab in frail and elderly patients with stage four non-small cell lung cancer: Study protocol of the randomized phase II DURATION trial.Trials 21/1:352.
Proctor T, Jensen K, Kieser M (2020). Integrated evaluation of targeted and non-targeted therapies in a network meta-analysis.Biom J 62/3:777-789.
Seide S.E, Jensen K, Kieser M (2020). A comparison of Bayesian and frequentist methods in random-effects network meta-analysis of binary data.Res Synth Methods 11/3:363-378.
Zapf A, Rauch G, Kieser M (2020). Why do you need a biostatistician?.BMC Med Res Methodol 20/1:23.
Zimmermann G, Kieser M, Bathke A.C (2020). Sample size calculation and blinded recalculation for analysis of covariance models with multiple random covariates.J Biopharm Stat 30/1:143-159.
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2019
Arians N, Kieser M, Benner L, Rochet N, Schroder L, Katayama S, Herfarth K, Schubert K, Schneeweiss A, Sohn C, Lindel K, Debus J (2019). Adjuvant intensity modulated whole-abdominal radiation therapy for high-risk patients with ovarian cancer FIGO stage III: final results of a prospective phase 2 study.Radiat Oncol 14/1:179.
Bozorgmehr F, Hommertgen A, Krisam J, Lasitschka F, Kuon J, Maenz M, Huber P.E, Konig L, Kieser M, Debus J, Thomas M, Rieken S (2019). Fostering efficacy of anti-PD-1-treatment: Nivolumab plus radiotherapy in advanced non-small cell lung cancer - study protocol of the FORCE trial.BMC Cancer 19/1:1074.
Caliebe A, Burger H.U, Knoerzer D, Kieser M (2019). Big Data in der klinischen Forschung.Deutsches Ärzteblatt International 116/35-36:1534-1539.
Christiansen H, Reck C, Zietlow A.L, Otto K, Steinmayr R, Wirthwein L, Weigelt S, Stark R, Ebert D.D, Buntrock C, Krisam J, Klose C, Kieser M, Schwenck C (2019). Children Of Mentally Ill Parents at Risk Evaluation (COMPARE): Design and Methods of a Randomized Controlled Multicenter Study – Part I.Frontiers in Psychiatry 10.
El Shafie R.A, Paul A, Bernhardt D, Lang K, Welzel T, Sprave T, Hommertgen A, Krisam J, Schmitt D, Klüter S, Schubert K, Klose C, Kieser M, Debus J, Rieken S (2019). Robotic radiosurgery for brain metastases diagnosed with either SPACE or MPRAGE sequence (CYBER-SPACE) – A single-center prospective randomized trial.Neurosurgery 84/1:253–260.
Feisst M, Heil J, Stolpner I, von Au A, Domschke C, Sohn C, Kieser M, Rauch G, Hennigs A (2019). Psychometric validation of the Breast Cancer Treatment Outcome Scale (BCTOS-12): a prospective cohort study.Arch Gynecol Obstet 300/6:1679-1686.
Feißt M, Hennigs A, Heil J, Moosbrugger H, Kelava A, Stolpner I, Kieser M, Rauch G (2019). Refining scores based on patient reported outcomes statistical and medical perspectives.BMC Medical Research Methodology 19.
Frese C, Wohlrab T, Sheng L, Kieser M, Krisam J, Wolff D (2019). Clinical effect of stannous fluoride and amine fluoride containing oral hygiene products: A 4-year randomized controlled pilot study.Scientific Reports 9/1.
Fuhrer H, Schönenberger S, Niesen W.D, Seide S, Meyne J, Gerner S.T, Vollmuth C, Beck C, Meckel S, Schocke M, Wodarg F, Huttner H.B, Möhlenbruch M.A, Kieser M, Ringleb P, Neugebauer H (2019). Endovascular stroke treatment’s impact on malignant type of edema (ESTIMATE).Journal of Neurology 266/1:223-231.
König L, Dreyling M, Dürig J, Engelhard M, Hohloch K, Viardot A, Witzens-Harig M, Kieser M, Klapper W, Pott C, Herfarth K (2019). Therapy of nodal Follicular Lymphoma (WHO grade 1/2) in clinical stage I/II using response adapted Involved Site Radiotherapy in combination with Obinutuzumab (Gazyvaro) - GAZAI Trial (GAZyvaro and response adapted Involvedsite Radiotherapy): a study protocol for a single-arm, non-randomized, open, national, multi-center phase II trial.Trials 20.
Mendes Jorge M, Ouermi L, Meissner P, Compaore G, Coulibaly B, Nebie E, Krisam J, Klose C, Kieser M, Jahn A, Lu G, U D.A, Sie A, Mockenhaupt F.P, Muller O (2019). Safety and efficacy of artesunate-amodiaquine combined with either methylene blue or primaquine in children with falciparum malaria in Burkina Faso: A randomized controlled trial.PLoS One 14/10:e0222993.
Meyding-Lamadé U, Jacobi C, Martinez-Torres F, Lenhard T, Kress B, Kieser M, Klose C, Einhäupl K.M, Boesel J, Koennecke H.C, Homberg V, Weishaupt G, Claus D, Kieseier B, Bardutzky J, Steinmetz H, Lorenz M, Neuman-Haefelin T, Gerloff C, Stingele R, Schneider D, Grau A, Sander A, Luntz S, Hoppe-Tichy T, Hanley D, von Kummer R, Craemer E.M (2019). The German trial on Acyclovir and Corticosteroids in Herpes-simplex-virus-Encephalitis (GACHE): a multicenter, randomized, double-blind, placebo-controlled trial.Neurological Research and Practice 1.
Oldenhof H, Prätzlich M, Ackermann K, Baker R, Batchelor M, Baumann S, Bernhard A, Clanton R, Dikeos D, Dochnal R, Fehlbaum L.V, Fernández-Rivas A, de Geusk E, Gonzalez K, González de Artaza-Lavesa M, Guijarro S, Gundlach M, Herpertz-Dahlmann B, Hervas A, Jansen L, Kersten L, Kohls G, Konsta A, Lazaratou H, Kerexeta-Lizeaga I, Martinelli A, van Nimwegen T, Puzzo I, Raschle N.M, Rogers J, Siklósi R, Smaragdi A, Steppan M, De Brito S, Fairchild G, Kieser M, Konrad K, Freitag C, Stadler C, Popma A (2019). Baseline autonomic nervous system activity in female children and adolescents with conduct disorder: Psychophysiological findings from the FemNAT-CD study.Journal of Criminal Justice 65.
Pilz M, Kunzmann K, Herrmann C, Rauch G, Kieser M (2019). A variational approach to optimal two-stage designs.Statistics in Medicine 38/21:4159-4171.
Prätzlich M, Oldenhof H, Steppan M, Jansen L, Raschle N.M, Kersten L, Fehlbaum L.V, Menks W.M, Vriends N, Gonzalez K, Smaragdi A, Puzzo I, Batchelor M, Rogers J, Clanton R, Baker R, Bernhard A, Martinelli A, Ackermann K, Baumann S, Gundlach M, Kohls G, González de Artaza-Lavesa M, Kerexeta-Lizeaga I, Fernández-Rivas A, Dochnal R, Kirchner M, Lazaratou H, Dikeos D, Konsta A, Siklósi R, Herpertz-Dahlmann B, Konrad K, Freitag C, De Brito S, Fairchild G, Kieser M, Popma A, Stadler C (2019). Resting autonomic nervous system activity and dimensions of antisocial behaviour assessed cross-sectionally. Findings from the European multi-centre FemNAT-CD study.Journal of Criminal Justice 65.
Preussler S, Kieser M, Kirchner M (2019). Optimal sample size allocation and go/no-go decision rules for phase II/III programs where several phase III trials are performed.Biometrical Journal 61/2:357-378.
Ronellenfitsch U, Jensen K, Seide S, Kieser M, Schwarzbach M, Slanger T.E, Burmeister B, Kelsen D, Niedzwiecki D, Piessen G, Schuhmacher C, Urba S, van de Velde C, Ychou M, Hofheinz R, Lorenzen S (2019). Disease-free survival as a surrogate for overall survival in neoadjuvant trials of gastroesophageal adenocarcinoma: Pooled analysis of individual patient data from randomised controlled trials.Eur J Cancer 123:101-111.
Schonenberger S, Henden P.L, Simonsen C.Z, Uhlmann L, Klose C, Pfaff J.A.R, Yoo A.J, Sorensen L.H, Ringleb P.A, Wick W, Kieser M, Mohlenbruch M.A, Rasmussen M, Rentzos A, Bosel J (2019). Association of General Anesthesia vs Procedural Sedation With Functional Outcome Among Patients With Acute Ischemic Stroke Undergoing Thrombectomy: A Systematic Review and Meta-analysis.Jama 322/13:1283-1293.
Seide S, Jensen K, Kieser M (2019). Simulation and data-generation for random-effects network meta-analysis of binary outcome.Statistics in Medicine 38/17:3288-3303.
Stracke M, Gilbert K, Kieser M, Klose C, Krisam J, Ebert D.D, Buntrock C, Christiansen H (2019). COMPARE Family (Children of Mentally Ill Parents at Risk Evaluation): A Study Protocol for a Preventive Intervention for Children of Mentally Ill Parents (Triple P, Evidence-Based Program That Enhances Parentings Skills, in Addition to Gold-Standard CBT With the Mentally Ill Parent) in a Multicenter RCT - Part II.Frontiers in Psychiatry 10.
Weber D, Uhlmann L, Schönenberger S, Kieser M (2019). Adaptive propensity score procedure improves matching in prospective observational trials.BMC Medical Research Methodology 19.
Zapf A, Hübner M, Rauch G, Kieser M (2019). What makes a biometrician?.Statistics in Medicine 38/4:695-701.
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2018
Beckmann L, Grouven U, Kieser M, Sieben W, Skipka G, Bender R (2018). Untersuchung von Methoden zur Überprüfbarkeit von Ergebnissen von Studienpopulationen auf Teilpopulationen.GMS Medizinische Informatik, Biometrie und Epidemiologie 14/2.
Benner L, Kieser M (2018). Timing of the interim analysis in adaptive enrichment designs.Journal of Biopharmaceutical Statistics 28/4:622-632.
Bernhardt D, Hommertgen A, Schmitt D, El Shafie R, Paul A, Koenig L, Mair-Walther J, Krisam J, Klose C, Welzel T, Hoerner-Rieber J, Kappes J, Thomas M, Heussel C.P, Steins M, Kieser M, Debus J, Rieken S (2018). Whole brain radiation therapy (WBRT) alone versus radiosurgery (SRS) for patients with 1-10 brain metastases from small cell lung cancer (ENCEPHALON Trial): study protocol for a randomized controlled trial.Trials 19.
El Shafie R.A, Paul A, Bernhardt D, Hauswald H, Welzel T, Sprave T, Hommertgen A, Krisam J, Schmitt D, Klüter S, Schubert K, Klose C, Kieser M, Debus J, Rieken S (2018). Evaluation of Stereotactic Radiotherapy of the Resection Cavity after Surgery of Brain metastases compared to post-operative whole-brain radiotherapy (ESTRON) – A single-center prospective randomized trial.Neurosurgery 83/3:566-573.
Freitag C.M, Konrad K, Stadler C, De Brito S.A, Popma A, Herpertz S.C, Herpertz-Dahlmann B, Neumann I, Kieser M, Chiocchetti A.G, Schwenck C, Fairchild G (2018). Conduct disorder in adolescent females: current state of research and study design of the FemNAT-CD consortium.European Child & Adolescent Psychiatry 27/9:1077-1093.
Frese C, Wohlrab T, Sheng L, Kieser M, Krisam J, Frese F, Wolff D (2018). Clinical management and prevention of dental caries in athletes: A four-year randomized controlled clinical trial.Scientific Reports 8/16991.
Greiner S, Jud A, Aurich M, Geisenberger C, Uhlmann L, Hilbel T, Kieser M, Katus H.A, Mereles D (2018). Prognostic relevance of elevated pulmonary arterial pressure assessed non-invasively: Analysis in a large patient cohort with invasive measurements in near temporal proximity.PLOS ONE 13/1.
Grund S, Mettlach M, Rath K, Kieser M, Schäfer H.G (2018). Ergebnisvergleich von multimorbiden gefäßchirurgischen Patienten mit und ohne Majoramputation in einer deutschen stationären geriatrischen Rehabilitationsklinik.Zeitschrift für Gerontologie und Geriatrie 51/3:335-342.
Kieser M, Kirchner M, Dölger E, Götte H (2018). Optimal planning of phase II/III programs for clinical trials with multiple endpoints.Pharmaceutical Statistics 17/5:437-457.
Knahl S.I.E, Lang B, Fleischer F, Kieser M (2018). A comparison of group sequential and fixed sample size designs for bioequivalence trials with highly variable drugs.European Journal of Clinical Pharmacology 74/5:549-559.
Kunzmann K, Kieser M (2018). Test-compatible confidence intervals for adaptive two-stage single-arm designs with binary endpoint.Biometrical Journal 60/1:196-206.
Mayer J.S, Hees K, Medda J, Grimm O, Asherson P, Bellina M, Colla M, Ibáñez P, Koch E, Martinez-Nicolas A, Muntaner-Mas A, Rommel A, Rommelse N, de Ruiter S, Ebner-Priemer U.W, Kieser M, Ortega F.B, Thome J, Buitelaar J.K, Kuntsi J, Ramos-Quiroga J.A, Reif A, Freitag C.M (2018). Bright light therapy versus physical exercise to prevent co-morbid depression and obesity in adolescents and young adults with attention-deficit / hyperactivity disorder: study protocol for a randomized controlled trial.Trials 19.
Mundiyanapurath S, Hees K, Ahmed N, Wahlgren N, Uhlmann L, Kieser M, Ringleb P.A, Hacke W, Nagel S (2018). Predictors of Symptomatic Intracranial Hemorrhage in Off-label Thrombolysis: an Analysis of the SITS registry.European Journal of Neurology 25/2:340-347.
Ozga A.K, Kieser M, Rauch G (2018). A systematic comparison of recurrent event models for application to composite endpoints.BMC Medical Research Methodology 18.
Rauch G, Brannath W, Brückner M, Kieser M (2018). The average hazard ratio a good effect measure for time-to-event endpoints when the proportional hazard assumption is violated?.Methods of Information in Medicine 51/3:89-100.
Rauch G, Kieser M, Binder H, Bayes‑Genis A, Jahn-Eimermacher A (2018). Time-to-first-event versus recurrent-event analysis: points to consider for selecting a meaningful analysis strategy in clinical trials with composite endpoints.Clinical Research in Cardiology 107/5:437-443.
Rauch G, Kunzmann K, Kieser M, Wegscheider K, König J, Eulenburg C (2018). A weighted combined effect measure for the analysis of a composite time-to-first-event endpoint with components of different clinical relevance.Statistics in Medicine 37/5:749-767.
Schönenberger S, Uhlmann L, Ungerer M, Pfaff J, Nagel S, Klose C, Bendszus M, Wick W, Ringleb P, Kieser M, Moehlenbruch M, Bösel J (2018). Association of blood pressure with functional outcome after stroke thrombectomy - post hoc analysis of the SIESTA trial.Stroke 49/6:1451-1456.
Stahl M, Müller F.M, Holfelder C.T, Kneppo C, Kieser M, Kasperk C, Schoenau E, Sommerburg O, Tönshoff B (2018). Multiple prevalent fractures in relation to macroscopic bone architecture in patients with cystic fibrosis. Epublished ahead of print Journal of Cystic Fibrosis.Journal of Cystic Fibrosis 17/1:114-120.
Uhlmann L, Jensen K, Kieser M (2018). Hypothesis testing in Bayesian network meta-analysis.BMC Medical Research Methodology 18/128.
Zylla M.M, Hillmann H.A.K, Proctor T, Kieser M, Scholz E, Zitron E, Katus H.A, Thomas D (2018). Use of the wearable cardioverter‑defibrillator (WCD) and WCD‑based remote rhythm monitoring in a real‑life patient cohort.Heart and Vessels 33/11:1390-1402.
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2017
Arians N, Kieser M, Benner L, Rochet N, Katayama S, Sterzing F, Herfarth K, Schubert K, Schroeder L, Schneeweiss A, Sohn C, Debus J, Lindel K (2017). Adjuvant intensity-modulated whole abdominal radiotherapy for high-risk patients with ovarian cancer FIGO stage III– first results of a prospective phase-II-study.International Journal of Radiation Oncology Biology Physics 99/4:912-920.
Diener M.K, Hüttner F.J, Kieser M, Knebel P, Dörr-Harim C, Distler M, Grützmann R, Wittel U.A, Schirren R, Hau H.M, Kleespies A, Heidecke C.D, Tomazic A, Halloran C.M, Wilhelm T.J, Bahra M, Beckurts T, Börner T, Glanemann M, Steger U, Treitschke F, Staib L, Thelen K, Bruckner T, Mihaljevic A.L, Werner J, Ulrich A, Hackert T, Büchler M.W (2017). Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial.Lancet 390:1028-1037.
Götte H, Kirchner M, Sailer M.O, Kieser M (2017). Simulation-based adjustment after exploratory biomarker subgroup selection in phase II.Statistics in Medicine 26/15:2378-2390.
Hajda J, Lehmann M, Krebs O, Kieser M, Geletneky K, Jäger D, Dahm M, Huber B, Schöning T, Sedlaczek O, Stenzinger A, Halama N, Daniel V, Leuchs B, Angelova A, Rommelaere J, Engeland C.E, Springfeld C, Ungerechts G (2017). A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol.BMC Cancer 17.
Hees K, Kieser M (2017). Blinded sample size recalculation in clinical trials incorporating historical data.Contemporary Clinical Trials 63:2-7.
Kersten L, Vriends N, Steppan M, Raschle N.M, Praetzlich M, Oldenhof H, Vermeiren R, Jansen L, Ackermann K, Bernhard A, Martinelli A, Gonzalez-Madruga K, Puzzo I, Wells A, Rogers J.C, Clanton R, Baker R.H, Grisley L, Baumann S, Gundlach M, Kohls G, Gonzalez-Torres M.A, Sesma-Pardo E, Dochnal R, Lazaratou H, Kalogerakis Z, Bigorra-Gualba A, Smaragdi A, Siklosi R, Dikeos D.G, Hervas A, Fernandez-Rivas A, De Brito S.A, Konrad K, Herpertz-Dahlmann B, Fairchild G, Freitag C.M, Popma A, Kieser M, Stadler S (2017). Community Violence Exposure and Conduct Problems in Children and Adolescents with Conduct Disorder and Healthy Controls.Frontiers in Behavioral Neuroscience 11.
Kieser M, Wirths M, Englert S, Kunz C.U, Rauch G (2017). OneArmPhaseTwoStudy: An R package for planning, conducting, and analysing single-arm phase II studies.Journal of Statistical Software 81/8.
Krisam J, Kieser M (2017). Optimal interim decision rules based on a binary surrogate outcome for adaptive biomarker-based trials in oncology.Statistics in Biopharmaceutical Research 9/4:321-332.
Kunz C.U, Wason J.M.S, Kieser M (2017). Two-stage phase II oncology designs using short-term endpoints for early stopping.Statistical Methods in Medical Research 26/4:1671-1683.
Kunzmann K, Benner L, Kieser M (2017). Point estimation in adaptive enrichment designs.Statistics in Medicine 36/25:3935-3947.
Kunzmann K, Kieser M (2017). Point estimation and p values in phase II adaptive two-stage designs with binary endpoint.Statistics in Medicine 36/6:971-984.
Luik A, Kunzmann K, Hörmann P, Schmidt K, Radzewitz A, Bramlage P, Schenk T, Schymik G, Merkel M, Kieser M, Schmitt C (2017). Cryoballoon vs. open irrigated radiofrequency ablation for paroxysmal atrial fibrillation: long-term FreezeAF outcomes.BMC Cardiovascular Disorders 17/135.
Ronellenfitsch U, Schwarzbach M, Hofheinz R, Kienle P, Nowak K, Kieser M, Slanger T.E, Burmeister B, Kelsen D, Niedzwiecki D, Schuhmacher C, Urba S, van de Velde S, Walsh T.N, Ychou M, Jensen K (2017). Predictors of overall and recurrence-free survival after neoadjuvant chemotherapy for gastroesophageal adenocarcinoma: pooled analysis of individual patient data (IPD) from randomized controlled trials (RCTs).European Journal of Surgical Oncology 43/8:1550-1558.
Sander A, Rauch G, Kieser M (2017). Blinded Sample Size Recalculation in Clinical Trials with Binary Composite Endpoints.Journal of Biopharmaceutical Statistics 27/4:705-715.
Schlenk R, Müller-Tidow C, Benner A, Kieser M (2017). Relapsed/refractory acute myeloid leukemia – any progress?.Current Opinion in Oncology 29/6:467-473.
Schönenberger S, Pfaff J, Uhlmann L, Klose C, Nagel S, Ringleb P.A, Hacke W, Kieser M, Bendszus M, Möhlenbruch M.A, Bösel J (2017). The impact of conscious sedation vs. general anesthesia for stroke thrombectomy on the predictive value of collateral status – a post hoc analysis of the SIESTA trial.American Journal of Neuroradiology 38/8:1580-1585.
Schüler S, Kieser M, Rauch G (2017). Choice of futility boundaries for group sequential designs with two endpoints.BMC Medical Research Methodology 17:119.
Uhlmann L, Jensen K, Kieser M (2017). Bayesian network meta-analysis for cluster randomized trials with binary outcomes.Research Synthesis Methods 8:236-250.
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2016
Englert S, Kieser M (2016). Letter to the editor: Comments on "Hypothesis testing for two-stage designs with over or under enrollment" by Donglin Zeng, Fei Gao, Kuolung Hu, Catherine Jiab and Joseph G. Ibrahim.Statistics in Medicine 35/9:1558-1559.
Freitag C.M, Jensen K, Elsuni L, Sachse M, Herpertz-Dahlmann B, Schulte-Rüther M, Hänig S, Gontard A. vo, Poustka L, Schad-Hansjosten T, Wenzl C, Sinzig J, Taurines R, Geißler J, Kieser M, Cholemkery H (2016). Group based cognitive behavioural psychotherapy for children and adolescents with Autism Spectrum Disorder: The randomised, multi-centre, controlled SOSTA - net trial.Journal of Child Psychology and Psychiatry 57/5:596-605.
Kieser M (2016). Statistical methods for the analysis of adverse event data.Pharmaceutical Statistics 15/4:290-291.
Kieser M, Stucke K (2016). Assessing additional benefit in noninferiority trials.Biometrical Journal 58:154-169.
Kirchner M, Kieser M, Götte H, Schüler A (2016). Utility-based optimization of phase II/III programs.Statistics in Medicine 35:305-316.
Krisam J, Kieser M (2016). Performance of biomarker-based subgroup selection rules in adaptive enrichment designs.Statistics in Biosciences 8/1:8-27.
Kunzmann K, Kieser M (2016). Optimal adaptive two-stage designs for single-arm trial with binary endpoint.arXiv :http://arxiv.org/abs/1605.00249.
Mundiyanapurath S, Stehr A, Wolf M, Kieser M, Möhlenbruch M, Bendszus M, Hacke W, Bösel J (2016). Pulmonary and circulatory parameter guided anesthesia in patients with ischemic stroke undergoing endovascular recanalization.Journal of Neurointerventional Surgery 8/4:335-341.
Pobiruchin M, Bochum S, Martens U.M, Kieser M, Schramm W (2016). Transition probabilities of HER2-positive and HER2-negative breast cancer patients treated with Trastuzumab obtained from a clinical cancer registry dataset.Data in Brief 7:654-657.
Pobiruchin M, Bochum S,Martens UM, Kieser M, Schramm W (2016). A method for using real world data in breast cancer modeling.Journal of Biomedical Informatics 60:385-394.
Probst P, Grummich K, Harnoss J.C, Hüttner F.J, Jensen K, Braun S, Kieser M, Ulrich A, Buechler M.W, Diener M.K (2016). Placebo-controlled trials in surgery: a systematic review and meta-analysis.Medicine 95/17:e3516.
Rauch G, Schüler S, Wirths M, Englert S, Kieser M (2016). Adaptive Designs for Two Candidate Primary Time-to-Event Endpoints.Statistics in Biopharmaceutical Research 8/2:207-216.
Reljic D, Feist J, Jost J, Kieser M, Friedmann-Bette B (2016). Rapid body mass loss affects erythropoiesis and hemolysis but does not impair aerobic performance in combat athletes.Scandinavian Journal of Medicine and Science in Sports 26/5:507-517.
Schmoor C, Bender R, Beyersmann J, Kieser M, Schumacher M (2016). Adverse event development in clinical oncology trials. Correspondence on Thanarajasingam G., Atherton PJ., Novotny PJ., Loprinzi C. L., Sloan J. A., Grothey A.: Longitudinal adverse event assessment in oncology clinical trials: The Toxicity over Time (ToxT) analysis of Alliance trials NCCTG N9741 and 979254. Lancet Oncology 2016; 17: 663-70.The Lancet Oncology 17/7:e263-e264.
Schönenberger S, Al-Suwaidan F, Kieser M, Uhlmann L, Bösel J (2016). The SETscore to predict tracheostomy need in cerebrovascular neurocritical care patients – a monocentric prospective validation study.Neurocritical Care 25/1:94-104.
Schönenberger S, Niesen W.D, Fuhrer H, Bauza C, Klose C, Kieser M, Suarez J, Seder D, Bösel J (2016). Early tracheostomy in ventilated stroke patients: Study protocol of the international multicentre randomized trial SETPOINT2 (Stroke-related Early Tracheotomy vs. Prolonged Orotracheal Intubation in Neurocritical care Trial 2).International Journal of Stroke 11/3:368-379.
Schönenberger S, Uhlmann L, Hacke W, Schieber S, Mundiyanapurath S, Purrucker J.C, Nagel S, Klose C, Pfaff J, Bendszus M, Ringleb P.A, Kieser M, Möhlenbruch M.A, Bösel J (2016). Effect of Conscious Sedation vs General Anesthesia on Early Neurological Improvement Among Patients With Ischemic Stroke Undergoing Endovascular Thrombectomy. A Randomized Clinical Trial.Jama 316/19:1986-1996.
Vllasaliu L, Jensen K, Hoss S, Landenberger M, Ufniarz K, Kieser M, Freitag C.M (2016). Diagnostic instruments for autism spectrum disorder (ASD): a systematic review and meta-analysis. Diagnostic Test Accuracy Protocol for Cochrane Review.Cochane Database of Systematic Reviews 2016/1.
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2015
Abel U, Jensen K, Karapanagiotou-Schenkel I, Kieser M (2015). Some issues of sample size calculation for time-to-event endpoints using the Freedman and Schoenfeld formulas.Journal of Biopharmaceutical Statistics 25:1285-1311.
Chaves G, Britez N, Munzinger J, Uhlmann L, Gonzalez G, Oviedo G, Chaparro V, Achon O, Bruckner T, Kieser M, Katus H.A, Mereles D (2015). Education to a Healthy Lifestyle Improves Symptoms and Cardiovascular Risk Factors - AsuRiesgo Study.Arquivos Brasileiros de Cardiologia 104/5:347-355.
Coulibaly B, Pritsch M, Bountogo M, Meissner P.E, Nebié E, Klose C, Kieser M, Berens-Riha N, Wieser A, Sirima S.B, Breitkreutz J, Schirmer R.H, Sié A, Mockenhaupt F.P, Drakeley C, Bousema T, Müller O (2015). Efficacy and safety of triple combination therapy with Artesunate-Amodiaquine-Methylene Blue for falciparum malaria in children: A randomized controlled trial in Burkina Faso.Journal of Infectious Disease 211/5:689-697.
Dugas M, Jöckel K.H, Friede T, Gefeller O, Kieser M, Marschollek M, Ammenwerth E, Röhrig R, Knaup-Gregori P, Prokosch H.U (2015). Memorandum "Open Metadata" Open access to documentation forms and item catalogs in healthcare.Methods of Information in Medicine 54/4:376-378.
Englert S, Kieser M (2015). Methods for proper handling of overrunning and underrunning in phase II designs for oncology trials.Statistics in Medicine 34/13:2128-2137.
Goette H, Schüler A, Kirchner M, Kieser M (2015). Sample size planning for phase II trials based on success probabilities for phase III.Pharmaceutical Statistics 14:515-524.
Häfner M.F, Lang K, Krug D, Koerber S.A, Uhlmann L, Kieser M, Debus J, Sterzing F (2015). Prognostic factors, patterns of recurrence and toxicity for patients with esophageal cancer undergoing definitive radiotherapy or chemo-radiotherapy.Journal of Radiation Research 56/4:742-749.
Hauswald H, Rieken S, Dienemann H.C, Thomas M, Kieser M, Debus J, Herfarth K (2015). Ion Therapy wihtin the Trimodal Management of Superior Sulcus Tumors: The INKA trial.BMC Cancer 15:192.
Kieser M, Englert S (2015). Performance of adaptive designs for single-armed phase II oncology trials.Journal of Biopharmaceutical Statistics 25/3:602-615.
Kieser M, Englert S, Rauch G (2015). Adaptive designs for Phase II oncology trials.Clinical Investigation 5/4:363-366.
Kieser M, Rauch G (2015). Two-stage designs for cross-over bioequivalence trials.Statistics in Medicine 34/16:2403-2416.
Krisam J, Kieser M (2015). Optimal Decision Rules for Biomarker-based Subgroup Selection for a Targeted Therapy in Oncology.International Journal of Molecular Sciences 16:10354-10375.
Luik A, Radzewitz A, Kieser M, Walter M, Bramlage P, Horn N, Brinkmeier-Theofanopoulou M, Kunzmann K, Hörmann P, Schmidt K, Riexinger T, Schymik G, Merkel M, Schmitt C (2015). Cryoballon versus open irrigated radiofrequency ablation in patients with paroxysmal atrial fibrillation: the prospective, randomized, controlled, non-inferiority FreezeAF study.Circulation 132:1311-1319.
Rath M.G, Uhlmann L, Heil J, Domschke C, Roth Z, Sinn H.P, Marme F, Scharf A, Schneeweiss A, Kieser M, Sohn C, Rom J (2015). Predictors of Residual Tumor in Breast-Conserving Therapy.Annals of Surgical Oncolology 22/Supplement:451–458.
Rath M.G, Uhlmann L, Heil J, Domschke C, Roth Z, Sinn H.P, Marme F, Scharf A, Schneeweiss A, Kieser M, Sohn C, Rom J (2015). Predictors of positive margins in breast-conserving therapy.Annals of Surgical Oncology 22:S451-S458.
Rauch G, Kieser M (2015). Adaptive designs in clinical trials with multiple endpoints.Clinical Investigation 5/5:433-435.
Rauch G, Rauch B, Schüler S, Kieser M (2015). Opportunities and challenges of clinical trials in cardiology using composite primary endpoints.World Journal of Cardiology 7:1-5.
Schönenberger S, Möhlenbruch M, Pfaff J, Mundiyanapurath S, Kieser M, Bendszus M, Hacke W, Bösel J (2015). Sedation vs. Intubation for Endovascular Stroke TreAtment (SIESTA) - a randomized monocentric trial.International Journal of Stroke 10:969-978.
Stock C, Uhlmann L, Hoffmeister M, Laux G, Kieser M, Brenner H (2015). Identification of physicians with unusual performance in screening colonoscopy databases: a Bayesian approach.Gastrointestinal Endoscopy 81/3:646-654.
Zylla M.M, Pohlmeier M, Hess A, Mereles D, Kieser M, Bruckner T, Scholz E, Zitron E, Schweizer P.A, Katus H.A, Thomas D (2015). Prevalence of Intracardiac Thrombi Under Phenprocoumon, Direct Oral Anticoagulants (Dabigatran and Rivaroxaban), and Bridging Therapy in Patients With Atrial Fibrillation and Flutter.American Journal of Cardiology 115/5:635-640.
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2014
Diener M.K, Knebel P, Kieser M, Probst P, Büchler M.W (2014). Correspondence Authors´reply: Antibiotic sutures against surgical site infections. Concerning: Effectiveness of triclosan-coated PDS Plus versus uncoated PDS II sutures for prevention of surgical site infection after abdominal wall closure: the randomised controlled PROUD trial by Dr. Tetsuji Fujita.Lancet 384/9952:1425-1426.
Diener M.K, Knebel P, Kieser M, Schüler P, Schiergens T.S, Atanassov V, Neudecker J, Stein E, Thielemann H, Kunz R, Frankenberg M. vo, Schernikau U, Bunse J, Jansen-Winkeln B, Partecke L.I, Prechtl G, Pochhammer J, Bouchard R, Hodina R, Beckurts K.T.E, Leißner L, Lemmens H.P, Kallinowski F, Thomusch O, Seehofer D, Simon T, Hyhlik-Dürr A, Seiler C.M, Hackert T, Reissfelder C, Hennig R, Doerr-Harim C, Klose C, Ulrich A, Büchler M.W (2014). Effectiveness of triclosan-coated PDS Plus versus uncoated PDS II sutures for prevention of surgical site infection after abdominal wall closure: the randomised controlled PROUD trial.Lancet 384/9938:142-152.
Dugas M, Jöckel K.H, Gefeller O, Knaup-Gregori P, Friede T, Ammenwerth E, Kieser M, Prokosch H.U (2014). Open access to documentation forms and item catalogs in healthcare. Memorandum “Open Metadata”.GMS Medizinische Informatik, Biometrie und Epidemiologie 10/1:1-4.
Golkowski D, Friede T, Kieser M (2014). Blinded sample size re-estimation in crossover bioequivalence trials.Pharmaceutical Statistics 13/3:157-162.
Kopf S, Oikonomou D, Eynatten M. vo, Kieser M, Zdunek D, Hess G, Morcos M, Forsblom C, Bierhaus A, Groop P.H, Nawroth P.P, Humpert P.M (2014). Urinary adiponectin is an independent predictor of decline ro renal function in type 2 diabetes.Acta Diabetologica 51/3:479-489.
Krisam J, Kieser M (2014). Decision rules for subgroup selection based on a predictive biomarker.Journal of Biopharmaceutical Statistics 24/1:188-202.
Kunz C, Kieser M (2014). Blinded versus unblinded covariate selection in confirmatory survival trials.Journal of Biopharmaceutical Statistics 24:398-414.
Rauch G, Jahn-Eimermacher A, Brannath W, Kieser M (2014). Opportunities and challenges of combined effect measures based on prioritized outcomes.Statistics in Medicine 33/7:1104-1120.
Rauch G, Kieser M, Ulrich S, Doherty P, Rauch B, Schneider S, Riemer T, Senges J (2014). Competing time-to-event endpoints in cardiology trials: A simulation study to illustrate the importance of an adequate statistical analysis.European Journal of Preventive Cardiology 21/1:74-80.
Rauch G, Wirtz M, Kieser M (2014). Consistency-adjusted alpha allocation methods for a time-to-event analysis of composite endpoints.Computational Statistics & Data Analysis 75/1:151-161.
Schmitz-Winnenthal F.H, Schmidt T, Beckhove P, Kieser M, Lehmann M, Dreger P, Büchler M.W (2014). Stem cell Transplantation for Eradication of Minimal PAncreatic Cancer persisting after surgical Excision (STEM PACE Trial, ISRCTN47877138) Study protocol for a phase I/II study.BMC Cancer 14/168:1-12.
Schüler S, Mucha A, Doherty P, Kieser M, Rauch G (2014). Easy applicable multiple testing procedures to improve the interpretation of clinical trials with composite endpoints.International Journal of Cardiology 175/1:126-132.
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2013
Combs S.E, Bruckner T, Mizoe J.E, Kamada T, Tsujii H, Kieser M, Debus J (2013). Comparison of carbon ion radiotherapy to photon radiation alone or in combination with temozolomide in patients with high-grade gliomas: Explorative hypothesis-generating retrospective analysis.Radiotherapy & Oncology 108/1:132-135.
Combs S.E, Habermehl D, Kieser M, Dreher C, Werner J, Haselmann R, Jäkel O, Jäger D, Büchler M.W, Debus J (2013). Phase I study evaluating the treatment of patients with locally advanced pancreatic cancer with carbon ion radiotherapy: the PHOENIX-01 trial.BMC Cancer 13/419:8.
Englert S, Kieser M (2013). Optimal adaptive two-stage designs for phase II cancer clinical trials.Biometrical Journal 55/6:955-968.
Freitag C.M, Cholemkery H, Elsuni L, Kröger A.K, Bender S, Kunz C.U, Kieser M (2013). The group-based social skills training SOSTA-FRA in children and adolescents with high functioning autism spectrum disorder - study protocol of the randomised, multi-centre controlled SOSTA-net trial.Trials 14/6:1-12.
Friede T, Kieser M (2013). Blinded sample size re-estimation in superiority and noninferiority trials: bias versus variance in variance estimation.Pharmaceutical Statistics 12/3:141-146.
Kieser M, Friede T, Gondan M (2013). Assessment of statistical significance and clinical relevance.Statistics in Medicine 32/10:1707-1719.
Klauß M, Stiller W, Pahn G, Fritz F, Kieser M, Werner J, Kauczor H.U, Grenacher L (2013). Dual-energy perfusion-CT of pancreatic adenocarcinoma.European Journal of Radiology 82/2:208-214.
Matthys H, Pliskevich D.A, Bondarchuk O.M, Malek F.A, Tribanek M, Kieser M (2013). Randomised, double-blind, placebo-controlled trial of EPs 7630 in adults with COPD.Respiratory Medicine 107/5:691-701.
Pobiruchin M, Kieser M (2013). Sample size calculation and blinded sample size recalculation in clinical trials where the treatment effect is measured by the relative risk.Communications in Statistics - Simulation & Computation 42/7:1643-1653.
Rauch G, Kieser M (2013). An expected power approach for the assessment of composite endpoints and their components.Computational Statistics & Data Analysis 60/1:111-122.
Röhmel J, Kieser M (2013). Investigations on non-inferiority - the Food and Drug Administration draft guidance on treatments for nosocomial pneumonia as a case for exact tests for binomial proportions.Statistics in Medicine 32/14:2335-2348.
Ronellenfitsch U, Schwarzbach M, Hofheinz R, Kienle P, Kieser M, Slanger T.E, Burmeister B, Kelsen D, Niedzwiecki D, Schuhmacher C, Urba S, van de Velde C, Walsh T.N, Ychou M, Jensen K (2013). Preoperative chemo(radio)therapy versus primary surgery for gastroesophageal adenocarcinoma: Systematic review with meta-analysis combining individual patient and aggregate data.European Journal of Cancer 49/15:3149-3158.
Ronellenfitsch U, Schwarzbach M, Hofheinz R, Kienle P, Kieser M, Slanger T.E, Jensen K (2013). Perioperative chemo(radio)therapy versus primary surgery for resectable adenocarcinoma of the stomach, gastroesophageal junction, and lower esophagus (Review).Cochrane Database of Systematic Reviews /5:1-85.
Stucke K, Kieser M (2013). Sample size calculations for noninferiority trials with Poisson distributed count data.Biometrical Journal 55/2:203-216.
Wachtlin D, Kieser M (2013). Blinded sample size recalculation in longitudinal clinical trials using generalized estimating equations.Therapeutic Innovation & Regulatory Science 47/4:460-467.
Wiegel T, Albers P, Bussar-Maatz R, Gottberg A, Härter M, Kieser M, Kristiansen G, Nettekoven G, Martus P, Schmidberger H, Wellek S, Stöckle M (2013). PREFERE - die Deutsche Prostatakrebsstudie.Urologe A 54/4:576-579.
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2012
Combs S.E, Kieser M, Habermehl D, Weitz J, Jäger D, Fossati P, Orrechia R, Engenhart-Cabillic R, Pötter R, Dosanjh M, Jäkel O, Büchler M.W, Debus J (2012). Phase I/II trial evaluating carbon ion radiotherapy for the treatment of recurrent rectal cancer: the PANDORA-01 trial.BMC Cancer 12/137:1-9.
Englert S, Kieser M (2012). Improving the Flexibility and Efficiency of Phase II Designs for Oncology Trials.Biometrics 68/3:886-892.
Englert S, Kieser M (2012). Adaptive designs for single-arm phase II trials in oncology.Pharmaceutical Statistics 11/3:241-249.
Gerlinger C, Edler L, Friede T, Kieser M, Nakas C.T, Schumacher M, Seldrup J, Victor N (2012). Considerations on what constitutes a 'qualified statistician' in regulatory guidelines.Statistics in Medicine 31/11-12:1303-1305.
Hartmann M, Kopf S, Kircher C, Faude-Lang V, Djuric Z, Augstein F, Friederich H.C, Kieser M, Bierhaus A, Humpert P.M, Herzog W, Nawroth P.P (2012). Sustained Effects of a Mindfulness-Based Stress-Reduction Intervention in Type 2 Diabetic Patients: Design and first results of a randomized controlled trial (The Heidelberger Diabetes and Stress Study).Diabetes Care 35/5:945-947.
Kamin W, Ilyenko L.I, Malek F.A, Kieser M (2012). Treatment of acute bronchitis with EPs 7630: Randomized, controlled trial in children and adolescents.Pediatrics International 54/2:219-226.
Klauß M, Stiller W, Fritz F, Kieser M, Werner J, Kauczor H.U, Grenacher L (2012). Computed tomography perfusion analysis of pancratic carcinoma.Journal of Computer Assisted Tomography 36/2:237-242.
Kunz C.U, Kieser M (2012). Estimation of secondary endpoints in two-stage phase II oncology trials.Statistics in Medicine 31/30:4352-4368.
Kunz C.U, Kieser M (2012). Curtailment in single-arm two-stage phase II oncology trials.Biometrical Journal 54/4:445-456.
Löffler T, Rossion I, Bruckner T, Diener M.K, Koch M, Frankenberg M. vo, Pochhammer J, Thomusch O, Kijak T, Simon T, Mihaljevic A.L, Krüger M, Stein E, Prechtl G, Hodina R, Michal W, Strunk R, Henkel K, Bunse J, Jaschke G, Politt D, Heistermann H.P, Fußer M, Lang C, Stamm A, Vosschulte A, Holzer R, Partecke L.I, Burdzik E, Hug H.M, Luntz S.P, Kieser M, Büchler M.W, Weitz J (2012). HAnd-Suture Versus STApling for Closure of Loop Ileostomy (HASTA Trial): Results of a Multicenter Randomized Trial (DRKS00000040).Annals of Surgery 256/5:828-836.
Rahbari N.N, Knebel P, Kieser M, Bruckner T, Bartsch D.K, Friess H, Mihaljevic A, Stern J, Diener M.K, Voss S, Rossion I, Büchler M.W, Seiler C.M (2012). Design and current status of CONTINT: continuous versus interrupted abdominal wall closure after emergency midline laparotomy - a randomized controlled multicenter trial NCT00544583.Trials 13/72:1-9.
Rahbari N.N, Lordick F, Fink C, Bork U, Stange A, Jäger D, Luntz S.P, Englert S, Rossion I, Koch M, Büchler M.W, Kieser M, Weitz J (2012). Resection of the primary tumour versus no resection prior to systemic therapy in patients with colon cancer and synchronous unresectable metastases UICC stage IV: SYNCHRONOUS - a randomised controlled multicentre trial ISRCTN30964555.BMC Cancer 12/142:1-11.
Rauch G, Kieser M (2012). Multiplicity adjustment for composite binary endpoints.Methods of Information in Medicine 51/4:309-317.
Rochon J, Gondan M, Kieser M (2012). To test or not to test: Preliminary assessment of normality when comparing two independent samples.BMC Medical Research Methodology 12:81.
Rothenhöfer S, Herrle F, Herold A, Joos A, Bussen D, Kieser M, Schiller P, Klose C, Seiler C.M, Kienle P, Post S (2012). DeloRes trial: study protocol for a randomized trial comparing two standardized surgical approaches in rectal prolapse - Delorme's procedure versus resection rectopexy.Trials 13/155:1-9.
Schiller P, Burchardi N, Niestroj M, Kieser M (2012). Quality of reporting of clinical non-inferiority and equivalence randomised trials - update and extension.Trials 13/214:1-12.
Stucke K, Kieser M (2012). A general approach for sample size calculation for the three-arm 'gold standard' non-inferiority design.Statistics in Medicine 31/28:3579-3596.
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2011
Diener M.K, Mehr K.T, Wente M.N, Kieser M, Büchler M.W, Seiler C.M (2011). Risk-benefit assessment of closed intra-abdominal drains after pancreatic surgery: a systematic review and meta-analysis assessing the current state of evidence.Langenbeck´s Archives of Surgery 396/1:41-52.
Diener M.K, Seiler C.M, Rossion I, Kleeff J, Glanemann M, Butturini G, Tomazic A, Bruns C.J, Busch O.R.C, Farkas S, Belyaev O, Neoptolemos J.P, Halloran C, Keck T, Niedergethmann M, Gellert K, Witzigmann H, Kollmar O, Langer P, Steger U, Neudecker J, Berrevoet F, Ganzera S, Heiss M.M, Luntz S.P, Bruckner T, Kieser M, Büchler M.W (2011). Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial.Lancet 377/9776:1514-1522.
Friede T, Kieser M (2011). Sample size reassessment in non-inferiority trials. Internal pilot study designs with ANCOVA.Methods of Information in Medicine 50/3:237-243.
Friede T, Kieser M (2011). Blinded sample size recalculation for clinical trials with normal data and baseline adjusted analysis.Pharmaceutical Statistics 10/1:8-13.
Heger U, Voss S, Knebel P, Doerr-Harim C, Neudecker J, Schuhmacher C, Faist E, Diener M.K, Kieser M, Seiler C.M, Büchler M.W (2011). Prevention of abdominal wound infection (PROUD trial, DRKS00000390): study protocol for a randomized controlled trial.Trials 12/245:1-10.
Kieser M, Friede T (2011). Autors' Reply to the Letter to the Editor by Gang Li concerning the article by M. Kieser and T. Friede: Planning and analysis of three-arm non-inferiority trials with binary endpoints. Statistics in Medicine,26:253-273,2007.Statistics in Medicine 30/3:300.
Knebel P, Lopez-Benitez R, Fischer L, Radeleff B.A, Stampfl U, Bruckner T, Hennes R, Kieser M, Kauczor H.U, Büchler M.W, Seiler C.M (2011). Insertion of Totally Implantable Venous Access Devices: An Expertise-Based, Randomized, Controlled Trial (NCT00600444).Annals of Surgery 253/6:111-117.
Kunz C.U, Kieser M (2011). Simon's minimax and optimal and Jung's admissible two-stage designs with or without curtailment.The Stata Journal 11/2:240-254.
Kunz C.U, Kieser M (2011). Optimal two-stage designs for single-arm phase II oncology trials with two binary endpoints.Methods of Information in Medicine 50/?:372-377.
Löffler T, Seiler C.M, Rossion I, Kijak T, Thomusch O, Hodina R, Krüger M, Simon T, Bruckner T, Kieser M, Büchler M.W, Weitz J (2011). Hand-suture versus stapling for closure of loop ileostomy: HASTA-Trial: a study rationale and design for a randomized controlled trial.Trials 12/43:1-10.
Rochet N, Kieser M, Sterzing F, Krause S, Lindel K, Harms W, Eichbaum M.H, Schneeweiss A, Sohn C, Debus J (2011). Phase II study evaluating consolidation whole abdominal intensity-modulated radiotherapy (IMRT) in patients with advanced ovarian cancer stage FIGO III - The OVAR-IMRT-02 Study.BMC Cancer 11/41:1-7.
Rochon J, Kieser M (2011). A closer look at the effect of preliminary goodness-of-fit testing for normality for the one-sample t-test.British Journal of Mathematical & Statistical Psychology 64/3:410-426.
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